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Toxin-neutralizing antibodies elicited by naturally acquired cutaneous anthrax are elevated following severe disease and appear to target conformational epitopes
Dumas, Eric K.; Demiraslan, Hayati; Ingram, Rebecca J.; Sparks, Rebecca M.; Muns, Emily; Zamora, Adriana; Larabee, Jason; Garman, Lori; Ballard, Jimmy D.; Boons, Geert-Jan; James, Judith A.; Darise Farris A.; Doganay, Mehmet; Darise Farris A. (Public Library of Science, 2020)Understanding immune responses to native antigens in response to natural infections can lead to improved approaches to vaccination. This study sought to characterize the humoral immune response to anthrax toxin components, ...