Başlık için Temel Tıp Bilimleri Bölümü / Department of Basic Medical Sciences listeleme
Toplam kayıt 51, listelenen: 1-20
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Aberrant miR-3135b and miR-1273g-3p expression in the peripheral blood samples of BRCA1/2 (±) ovarian cancer patients
(Elsevier Ltd, 2024)Ovarian cancer (OC) ranks as the eighth most prevalent malignancy among women globally. The short non-coding RNA molecules, microRNAs (miRNAs) target multiple mRNAs and regulate the gene expression. Here in this study, we ... -
Acute sleep deprivation: impairment of biventricular function assesed by speckle tracking echocardiography in healthy subjects
(SPRINGER HEIDELBERG, 2023)ObjectivesSleep deprivation (SD) has been found to be associated with an increased incidence of adverse cardiovascular disease (CVD) events. The aim of this study was to investigate whether or not acute SD has a pathological ... -
Analysis of changes in brain morphological structure of taekwondo athletes by diffusion tensor imaging
(ELSEVIER, 2023)Objective: Taekwondo, which is the most preferred sport among the martial arts, is known to improve individuals physically, spiritually and mentally. The aim of this study is to reveal the effect of teakwondo sport on the ... -
Anti-Inflammatory Effects of Melatonin in Rats with Induced Type 2 Diabetes Mellitus
(MDPI, 2022)Introduction: Insulin resistance is associated with a pro-inflammatory state increasing the risk for complications in patients with type 2 diabetes mellitus (T2DM). In addition to its chronobi-otic effects, the pineal ... -
Breast Cancer in East Africa: Prevalence and Spectrum of Germline SNV/Indel and CNVs in BRCA1 and BRCA2 Genes Among Breast Cancer Patients in Tanzania
(John Wiley and Sons Inc, 2022)Background: Growing prevalence and aggressiveness of breast cancer (BC) among East African women strongly indicate that the genetic risk factor implicated in the etiology of the disease may have a key role. Germline ... -
Breast Cancer Subtypes and Prognosis: Answers to Subgroup Classification Questions, Identifying the Worst Subgroup in Our Single-Center Series
(Dove Medical Press Ltd, 2022)Purpose: Many studies report the triple negative breast cancer (TNBC) as the worst subgroup, as such patients do not benefit from anti-hormonal therapy and human epidermal growth factor receptor 2 (HER2) antagonists. While ... -
Can the Gut Microbiota Serve as a Guide to the Diagnosis and Treatment of Childhood Epilepsy?
(Elsevier Inc., 2023)Background: To investigate the activity of the gut-brain axis in the pathogenesis of childhood epilepsy and to define biomarkers capable of assisting with determining new strategies in that context. Methods: Twenty children ... -
A Comparison of Automated Segmentation and Manual Tracing of Magnetic Resonance Imaging to Quantify Lateral Ventricle Volumes
(Kare Yayıncılık, 2022)Objective: Ventricular volume measurements have been proposed as a useful biomarker for several neurological diseases. The goal of this study was to compare the performance of 3 fully-automated tools, volBrain (http://vo ... -
COVID-19 Olası/Kesin Tanılı Hastalarda Serbest Radikal Ve Antioksidan Enzim Düzeylerinin Değerlendirilmesi
(DÜZCE ÜNİVERSİTESİ, 2023)Amaç: Koronavirüs hastalığı 2019 (COVID-19), küresel halk sağlığını tehdit eden ve bir pandemiye yol açan karmaşık bir hastalık olmasına rağmen, hastalığın patogenezinde yer alan pro-oksidan/oksidan dengesizliğinin katkıları ... -
Determining the Expression Levels of Circulating Tumour Cell Markers in Canine Mammary Tumours
(University of Veterinary and Pharmaceutical Sciences, 2021)Detection of the circulating tumour cells (CTC) in dogs with a mammary tumour is a useful tool to reveal the micrometastases long before metastases are recognised clinically. The aim of this study was to evaluate the ... -
Diyabet Hastalarının Kovid-19 Bilgi ve Korku Düzeyinin Tedbir Alma Üzerine Etkisi
(Fırat Üniversitesi Tıp Fakültesi, 2022)Amaç: Çalışmamızda Diabetes Mellitus (DM) hastalarının yeni tip koronavirüs (Kovid-19) hastalığı ile ilgili bilgi ve korku düzeyinin tedbir alma üzerine etkisini tespit etmek amaçlanmıştır. Gereç ve Yöntem: Tanımlayıcı ve ... -
DNA methylation of KIFC1 gene in determination of histological diagnosis, prognosis and metastasis of lung cancer
(ELSEVIER GMBH, 2023)Background: One of the main features of cancer, especially lung cancer (LC), is abnormal cell division. Abnormal expression of kinesin family member C1 (KIFC1/HSET), which is involved in mitotic cell division and ensures ... -
DNA REPAIR GENE OGG1 Ser326Cys POLYMORPHISM AND DNA DAMAGE IN PATIENTS WITH TYPE 2 DIABETES
(Academic Publishing House, 2022)8-hydroxydeoxyguanosine (8-OHdG) is the most frequent oxidative DNA damage. 8-oxo-deoxyguanosine DNA glycosylase 1 (OGG1) is involved in the repair of 8-OHdG. Many studies indicated that DNA repair is decreased in type 2 ... -
Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker on oxidative stress and metabolism of elements in kidney of STZ-induced diabetic rats
(Academic Press Inc., 2024)In diabetes, increased oxidative stress and impaired trace element metabolism play an important role in the pathogenesis of diabetic nephropathy. The objective of this research was to examine the outcomes of blocking the ... -
Effect of Breast Cancer and Brast Cancer Treatment on the Blood Serum Concentrations of Trace Elements and Selenoproteins
(Polish Society Magnesium Research, 2022)SciVal Topics Metrics Funding details Abstract Trace elements (TEs) playing critical roles in chemical events that occur at the cellular level in the body are necessary for biological processes in human health. The ... -
Effect of carnosine on ovarian follicle in rats exposed to electromagnetic field
(Sociedad Anatomica Espanola, 2022)The electromagnetic field (EMF) has an effect on various organs, including the female reproductive system. The purpose of this study was to evaluate the impact of carnosine on ovarian follicle number and diameter in rats ... -
Evaluating the brainstem in children with breathholding spells
(Kare Publishing, 2022)OBJECTIVE: Breath-holding spells (BHSs) are a non-epileptic paroxysmal phenomenon characterized by frequent apnea episodes, loss of consciousness, and changes in skin tone and postural tone triggered by negative stimuli ... -
Evaluation of BRCA1/2 Gene Mutations in Patients With High-Risk Breast and/or Ovarian Cancer in Turkey
(De Gruyter, 2022)Objectives To find BRCA1/2 test selection criteria unique to the Turkish population, as well as to provide the BRCA1/2 gene mutation distributions of patient population to the literature. Methods Genetic counseling was ... -
Evaluation of Cerebellar Volume in Adult Turkish Male Individuals: Comparison of three Methods in Magnetic Resonance Imaging
(Erciyes Univ., 2020)Objective: Cerebellum plays quite important in our balance by coordinating the control and synergistic movements of the skeletal muscles. There are many studies in which the volume of the cerebellum is measured and different ... -
EVALUATION OF THE HABIT OF READING NUTRITION LABELS IN CONSUMERS: CASE OF ELAZIĞ CITY
(Eskişehir Osmangazi University, 2022)This study, it was aimed to evaluate the nutrition label reading habits of adult consumers aged 18 and over, in Elazığ city center. This cross-sectional study consists of consumers who shop from the shopping malls in Elazığ ...
